Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline American Airlines

The cheapest airline(s) flying from Des Moines to Chicago is American Airlines.

  • American Airlines American Airlines
  • United Airlines United Airlines
  • Frontier Airlines Frontier Airlines
Cheapest Month No data available
No data available

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Cheapest Day of the Week Saturday

The cheapest day(s) of the week to fly from Des Moines to Chicago is Saturday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Sat, 2 Nov, 2024

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    • Airline Filter by Airline
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      • Availability
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      • 18:54 DSM
        20:22 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 18:54 - ORD 20:22 1h 28m Direct
      • DSMDes Moines Airport 18:54
      • ORDChicago O'Hare International Airport 20:22
      • 1h 28m
      • Direct
      • United Airlines (UA 1807)Airbus
      • United Airlines (UA 1807)
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      • 18:54 DSM
        20:25 ORD
        1Hrs, 31m Direct
      • DSMDes Moines Airport 18:54 - ORD 20:25 1h 31m Direct
      • DSMDes Moines Airport 18:54
      • ORDChicago O'Hare International Airport 20:25
      • 1h 31m
      • Direct
      • United Airlines (UA 5599)Embraer 175
      • United Airlines (UA 5599)
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      • Embraer 175
      • 18:54 DSM
        20:22 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 18:54 - ORD 20:22 1h 28m Direct
      • DSMDes Moines Airport 18:54
      • ORDChicago O'Hare International Airport 20:22
      • 1h 28m
      • Direct
      • United Airlines (UA 1807)Airbus
      • United Airlines (UA 1807)
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      • Airbus
      • 05:20 DSM
        06:52 ORD
        1Hrs, 32m Direct
      • DSMDes Moines Airport 05:20 - ORD 06:52 1h 32m Direct
      • DSMDes Moines Airport 05:20
      • ORDChicago O'Hare International Airport 06:52
      • 1h 32m
      • Direct
      • American Airlines (AA 6389)Crj 700 Canadair Regional
      • American Airlines (AA 6389)
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      • Crj 700 Canadair Regional
      • 08:00 DSM
        09:27 ORD
        1Hrs, 27m Direct
      • DSMDes Moines Airport 08:00 - ORD 09:27 1h 27m Direct
      • DSMDes Moines Airport 08:00
      • ORDChicago O'Hare International Airport 09:27
      • 1h 27m
      • Direct
      • United Airlines (UA 1363)Boeing 737 800
      • United Airlines (UA 1363)
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      • Boeing 737 800
      • 11:25 DSM
        12:53 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 11:25 - ORD 12:53 1h 28m Direct
      • DSMDes Moines Airport 11:25
      • ORDChicago O'Hare International Airport 12:53
      • 1h 28m
      • Direct
      • United Airlines (UA 2306)Airbus
      • United Airlines (UA 2306)
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      • Airbus
      • 11:25 DSM
        12:53 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 11:25 - ORD 12:53 1h 28m Direct
      • DSMDes Moines Airport 11:25
      • ORDChicago O'Hare International Airport 12:53
      • 1h 28m
      • Direct
      • United Airlines (UA 2306)Airbus
      • United Airlines (UA 2306)
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      • 11:25 DSM
        12:56 ORD
        1Hrs, 31m Direct
      • DSMDes Moines Airport 11:25 - ORD 12:56 1h 31m Direct
      • DSMDes Moines Airport 11:25
      • ORDChicago O'Hare International Airport 12:56
      • 1h 31m
      • Direct
      • United Airlines (UA 3597)Embraer 170
      • United Airlines (UA 3597)
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      • Embraer 170
      • 11:25 DSM
        12:56 ORD
        1Hrs, 31m Direct
      • DSMDes Moines Airport 11:25 - ORD 12:56 1h 31m Direct
      • DSMDes Moines Airport 11:25
      • ORDChicago O'Hare International Airport 12:56
      • 1h 31m
      • Direct
      • United Airlines (UA 3597)Embraer 175
      • United Airlines (UA 3597)
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      • Embraer 175
      • 11:44 DSM
        13:15 ORD
        1Hrs, 31m Direct
      • DSMDes Moines Airport 11:44 - ORD 13:15 1h 31m Direct
      • DSMDes Moines Airport 11:44
      • ORDChicago O'Hare International Airport 13:15
      • 1h 31m
      • Direct
      • American Airlines (AA 4703)Embraer Emb 175
      • American Airlines (AA 4703)
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      • Embraer Emb 175
      • 11:50 DSM
        13:21 ORD
        1Hrs, 31m Direct
      • DSMDes Moines Airport 11:50 - ORD 13:21 1h 31m Direct
      • DSMDes Moines Airport 11:50
      • ORDChicago O'Hare International Airport 13:21
      • 1h 31m
      • Direct
      • American Airlines (AA 4703)Embraer Emb 175
      • American Airlines (AA 4703)
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      • Embraer Emb 175
      • 15:20 DSM
        16:51 ORD
        1Hrs, 31m Direct
      • DSMDes Moines Airport 15:20 - ORD 16:51 1h 31m Direct
      • DSMDes Moines Airport 15:20
      • ORDChicago O'Hare International Airport 16:51
      • 1h 31m
      • Direct
      • United Airlines (UA 3457)Embraer 175
      • United Airlines (UA 3457)
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      • Embraer 175
      • 15:20 DSM
        16:48 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 15:20 - ORD 16:48 1h 28m Direct
      • DSMDes Moines Airport 15:20
      • ORDChicago O'Hare International Airport 16:48
      • 1h 28m
      • Direct
      • United Airlines (UA 1568)Airbus
      • United Airlines (UA 1568)
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      • 17:09 DSM
        18:40 ORD
        1Hrs, 31m Direct
      • DSMDes Moines Airport 17:09 - ORD 18:40 1h 31m Direct
      • DSMDes Moines Airport 17:09
      • ORDChicago O'Hare International Airport 18:40
      • 1h 31m
      • Direct
      • American Airlines (AA 4703)Embraer Emb 175
      • American Airlines (AA 4703)
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      • Embraer Emb 175
      • 17:16 DSM
        18:50 ORD
        1Hrs, 34m Direct
      • DSMDes Moines Airport 17:16 - ORD 18:50 1h 34m Direct
      • DSMDes Moines Airport 17:16
      • ORDChicago O'Hare International Airport 18:50
      • 1h 34m
      • Direct
      • American Airlines (AA 6047)Crj Canadair Regional
      • American Airlines (AA 6047)
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      • Crj Canadair Regional
      • 18:25 DSM
        23:05 MDW
        4Hrs, 40m 1 Stop (STL)
      • DSMDes Moines Airport 18:25 - MDW 23:05 4h 40m 1 Stop (STL) Saint Louis
      • DSMDes Moines Airport 18:25
        STLSt Louis Lambert Intl Airport 21:55
      • STLSt Louis Lambert Intl Airport 19:30
        MDWChicago Midway Airport 23:05
      • 4h 40m (2h 25m)
      • 1 Stop STL · Saint Louis 2h 25m
      • Southwest Airlines (WN 2925)Boeing 737 700
        Southwest Airlines (WN 652)Boeing 737 800
      • Southwest Airlines (WN 2925)
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      • 06:50 DSM
        11:50 MDW
        5Hrs, 00m 1 Stop (STL)
      • DSMDes Moines Airport 06:50 - MDW 11:50 5h 1 Stop (STL) Saint Louis
      • DSMDes Moines Airport 06:50
        STLSt Louis Lambert Intl Airport 10:40
      • STLSt Louis Lambert Intl Airport 08:05
        MDWChicago Midway Airport 11:50
      • 5h (2h 35m)
      • 1 Stop STL · Saint Louis 2h 35m
      • Southwest Airlines (WN 372)Boeing 737 700
        Southwest Airlines (WN 2364)Boeing 737 800
      • Southwest Airlines (WN 372)
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      • 16:10 DSM
        20:05 MDW
        3Hrs, 55m 1 Stop (STL)
      • DSMDes Moines Airport 16:10 - MDW 20:05 3h 55m 1 Stop (STL) Saint Louis
      • DSMDes Moines Airport 16:10
        STLSt Louis Lambert Intl Airport 18:55
      • STLSt Louis Lambert Intl Airport 17:15
        MDWChicago Midway Airport 20:05
      • 3h 55m (1h 40m)
      • 1 Stop STL · Saint Louis 1h 40m
      • Southwest Airlines (WN 2925)Boeing 737 800
        Southwest Airlines (WN 1253)Boeing 737 700
      • Southwest Airlines (WN 2925)
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      No Schedules Sorry, there are no schedules matching your filters. Try removing one. reset
      What’s the fastest flight time from Des Moines to Chicago?

      The fastest flight time for direct flights from Des Moines to Chicago is 1 hour 27 minutes. Check latest flight schedules & prices on Wego.

      What’s the most popular airline flying from Des Moines to Chicago?

      The most popular airline flying from Des Moines to Chicago is American Airlines. Find the latest flight deals on Wego.

      How far is Chicago from Des Moines?

      The flight distance between Des Moines and Chicago is 497km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 05:20. The last flight of the day departs at 18:25. See the full list of flight times on Wego.

      How many airlines offer direct flights from Des Moines to Chicago?

      There are 2 airlines that offer direct flights from Des Moines to Chicago. Find out the list of airlines on Wego.

      All Airports in Des Moines

      Des Moines Airport DSM

      Popular Airlines flying from Des Moines to Chicago

      American Airlines ‏()
      United Airlines ‏()

      Popular Destinations from Chicago

      Popular Destinations from Des Moines

      Popular Hotels in Chicago

      Hotels In Popular Destinations