Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline American Airlines

The cheapest airline(s) flying from Des Moines to San Diego is American Airlines.

  • American Airlines American Airlines
  • United Airlines United Airlines
  • Alaska Airlines Alaska Airlines
Cheapest Month April

Travel Period: December 2024 - November 2025

The cheapest month(s) to fly from Des Moines to San Diego is April.

  • Dec 2024
  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
Cheapest Day of the Week Tuesday

The cheapest day(s) of the week to fly from Des Moines to San Diego is Tuesday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Sat, 2 Nov, 2024

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      • Availability
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      • 18:15 DSM
        21:43 SAN
        5Hrs, 28m 1 Stop (PHX)
      • DSMDes Moines Airport 18:15 - SAN 21:43 5h 28m 1 Stop (PHX) Phoenix
      • DSMDes Moines Airport 18:15
        PHXPhoenix Sky Harbor Intl Airport 21:27
      • PHXPhoenix Sky Harbor Intl Airport 20:22
        SANSan Diego International Airport 21:43
      • 5h 28m (1h 05m)
      • 1 Stop PHX · Phoenix 1h 05m
      • American Airlines (AA 2158)Airbus
        American Airlines (AA 559)Airbus
      • American Airlines (AA 2158)
        • M
        • -
        • -
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        • F
        • -
        • S
      • 18:25 DSM
        22:05 SAN
        5Hrs, 40m 1 Stop (STL)
      • DSMDes Moines Airport 18:25 - SAN 22:05 5h 40m 1 Stop (STL) Saint Louis
      • DSMDes Moines Airport 18:25
        STLSt Louis Lambert Intl Airport 20:05
      • STLSt Louis Lambert Intl Airport 19:30
        SANSan Diego International Airport 22:05
      • 5h 40m (35m)
      • 1 Stop STL · Saint Louis 35m
      • Southwest Airlines (WN 2925)Boeing 737 700
        Southwest Airlines (WN 4198)Boeing 737 700
      • Southwest Airlines (WN 2925)
        • M
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        • S
      • 18:51 DSM
        23:56 SAN
        7Hrs, 05m 1 Stop (DEN)
      • DSMDes Moines Airport 18:51 - SAN 23:56 7h 05m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 18:51
        DENDenver Intl Airport 22:30
      • DENDenver Intl Airport 19:57
        SANSan Diego International Airport 23:56
      • 7h 05m (2h 33m)
      • 1 Stop DEN · Denver 2h 33m
      • Frontier Airlines (F9 1677)Airbus A320 Neo
        Frontier Airlines (F9 2711)Airbus A321 Neo
      • Frontier Airlines (F9 1677)
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      • 18:52 DSM
        23:56 SAN
        7Hrs, 04m 1 Stop (DEN)
      • DSMDes Moines Airport 18:52 - SAN 23:56 7h 04m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 18:52
        DENDenver Intl Airport 22:30
      • DENDenver Intl Airport 19:58
        SANSan Diego International Airport 23:56
      • 7h 04m (2h 32m)
      • 1 Stop DEN · Denver 2h 32m
      • Frontier Airlines (F9 1677)Airbus A320 Neo
        Frontier Airlines (F9 2711)Airbus A321 Neo
      • Frontier Airlines (F9 1677)
        • M
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      • 19:57 DSM
        23:56 SAN
        5Hrs, 59m 1 Stop (DEN)
      • DSMDes Moines Airport 19:57 - SAN 23:56 5h 59m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 19:57
        DENDenver Intl Airport 22:30
      • DENDenver Intl Airport 21:03
        SANSan Diego International Airport 23:56
      • 5h 59m (1h 27m)
      • 1 Stop DEN · Denver 1h 27m
      • Frontier Airlines (F9 1677)Airbus A321 Neo
        Frontier Airlines (F9 2711)Airbus A321 Neo
      • Frontier Airlines (F9 1677)
        • -
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      • 05:00 DSM
        08:52 SAN
        5Hrs, 52m 1 Stop (PHX)
      • DSMDes Moines Airport 05:00 - SAN 08:52 5h 52m 1 Stop (PHX) Phoenix
      • DSMDes Moines Airport 05:00
        PHXPhoenix Sky Harbor Intl Airport 08:34
      • PHXPhoenix Sky Harbor Intl Airport 07:09
        SANSan Diego International Airport 08:52
      • 5h 52m (1h 25m)
      • 1 Stop PHX · Phoenix 1h 25m
      • American Airlines (AA 1795)Airbus
        American Airlines (AA 1949)Airbus
      • American Airlines (AA 1795)
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        • S
      • 05:00 DSM
        10:08 SAN
        7Hrs, 08m 1 Stop (DFW)
      • DSMDes Moines Airport 05:00 - SAN 10:08 7h 08m 1 Stop (DFW) Dallas
      • DSMDes Moines Airport 05:00
        DFWDallas/Fort Worth Intl Airport 08:50
      • DFWDallas/Fort Worth Intl Airport 07:09
        SANSan Diego International Airport 10:08
      • 7h 08m (1h 41m)
      • 1 Stop DFW · Dallas 1h 41m
      • American Airlines (AA 2326)Airbus
        American Airlines (AA 384)Airbus
      • American Airlines (AA 2326)
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      • 05:00 DSM
        11:35 SAN
        8Hrs, 35m 1 Stop (PHX)
      • DSMDes Moines Airport 05:00 - SAN 11:35 8h 35m 1 Stop (PHX) Phoenix
      • DSMDes Moines Airport 05:00
        PHXPhoenix Sky Harbor Intl Airport 11:11
      • PHXPhoenix Sky Harbor Intl Airport 07:09
        SANSan Diego International Airport 11:35
      • 8h 35m (4h 02m)
      • 1 Stop PHX · Phoenix 4h 02m
      • American Airlines (AA 1795)Airbus
        American Airlines (AA 3105)Airbus
      • American Airlines (AA 1795)
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      • 05:20 DSM
        12:31 SAN
        9Hrs, 11m 1 Stop (ORD)
      • DSMDes Moines Airport 05:20 - SAN 12:31 9h 11m 1 Stop (ORD) Chicago
      • DSMDes Moines Airport 05:20
        ORDChicago O'Hare International Airport 10:05
      • ORDChicago O'Hare International Airport 06:52
        SANSan Diego International Airport 12:31
      • 9h 11m (3h 13m)
      • 1 Stop ORD · Chicago 3h 13m
      • American Airlines (AA 6389)Crj 700 Canadair Regional
        American Airlines (AA 2131)Boeing 737 800
      • American Airlines (AA 6389)
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      • 05:20 DSM
        12:33 SAN
        9Hrs, 13m 1 Stop (ORD)
      • DSMDes Moines Airport 05:20 - SAN 12:33 9h 13m 1 Stop (ORD) Chicago
      • DSMDes Moines Airport 05:20
        ORDChicago O'Hare International Airport 10:05
      • ORDChicago O'Hare International Airport 06:52
        SANSan Diego International Airport 12:33
      • 9h 13m (3h 13m)
      • 1 Stop ORD · Chicago 3h 13m
      • American Airlines (AA 6389)Crj 700 Canadair Regional
        American Airlines (AA 2131)Boeing 737 800
      • American Airlines (AA 6389)
        • M
        • -
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        • F
        • -
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      • 05:50 DSM
        12:00 SAN
        8Hrs, 10m 1 Stop (STL)
      • DSMDes Moines Airport 05:50 - SAN 12:00 8h 10m 1 Stop (STL) Saint Louis
      • DSMDes Moines Airport 05:50
        STLSt Louis Lambert Intl Airport 09:55
      • STLSt Louis Lambert Intl Airport 07:10
        SANSan Diego International Airport 12:00
      • 8h 10m (2h 45m)
      • 1 Stop STL · Saint Louis 2h 45m
      • Southwest Airlines (WN 372)Boeing 737 700
        Southwest Airlines (WN 4499)Boeing 737 700
      • Southwest Airlines (WN 372)
        • M
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        • -
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      • 06:00 DSM
        09:33 SAN
        5Hrs, 33m 1 Stop (DEN)
      • DSMDes Moines Airport 06:00 - SAN 09:33 5h 33m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 06:00
        DENDenver Intl Airport 08:05
      • DENDenver Intl Airport 07:04
        SANSan Diego International Airport 09:33
      • 5h 33m (1h 01m)
      • 1 Stop DEN · Denver 1h 01m
      • United Airlines (UA 497)Boeing 737 900
        United Airlines (UA 2309)Boeing 737 800
      • United Airlines (UA 497)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 06:00 DSM
        09:33 SAN
        5Hrs, 33m 1 Stop (DEN)
      • DSMDes Moines Airport 06:00 - SAN 09:33 5h 33m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 06:00
        DENDenver Intl Airport 08:05
      • DENDenver Intl Airport 07:04
        SANSan Diego International Airport 09:33
      • 5h 33m (1h 01m)
      • 1 Stop DEN · Denver 1h 01m
      • United Airlines (UA 497)Airbus
        United Airlines (UA 2309)Boeing 737 800
      • United Airlines (UA 497)
        • M
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      • 06:00 DSM
        09:33 SAN
        5Hrs, 33m 1 Stop (DEN)
      • DSMDes Moines Airport 06:00 - SAN 09:33 5h 33m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 06:00
        DENDenver Intl Airport 08:05
      • DENDenver Intl Airport 07:04
        SANSan Diego International Airport 09:33
      • 5h 33m (1h 01m)
      • 1 Stop DEN · Denver 1h 01m
      • United Airlines (UA 497)Boeing 737 800
        United Airlines (UA 2309)Boeing 737 800
      • United Airlines (UA 497)
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      • 06:00 DSM
        11:43 SAN
        7Hrs, 43m 1 Stop (DEN)
      • DSMDes Moines Airport 06:00 - SAN 11:43 7h 43m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 06:00
        DENDenver Intl Airport 10:15
      • DENDenver Intl Airport 07:04
        SANSan Diego International Airport 11:43
      • 7h 43m (3h 11m)
      • 1 Stop DEN · Denver 3h 11m
      • United Airlines (UA 497)Airbus
        United Airlines (UA 1842)Boeing 737 Max 9 Passenger
      • United Airlines (UA 497)
        • -
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      • 06:00 DSM
        11:48 SAN
        7Hrs, 48m 1 Stop (DEN)
      • DSMDes Moines Airport 06:00 - SAN 11:48 7h 48m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 06:00
        DENDenver Intl Airport 10:20
      • DENDenver Intl Airport 07:04
        SANSan Diego International Airport 11:48
      • 7h 48m (3h 16m)
      • 1 Stop DEN · Denver 3h 16m
      • United Airlines (UA 497)Airbus
        United Airlines (UA 1842)Boeing 737 900
      • United Airlines (UA 497)
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      • 06:00 DSM
        11:48 SAN
        7Hrs, 48m 1 Stop (DEN)
      • DSMDes Moines Airport 06:00 - SAN 11:48 7h 48m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 06:00
        DENDenver Intl Airport 10:20
      • DENDenver Intl Airport 07:04
        SANSan Diego International Airport 11:48
      • 7h 48m (3h 16m)
      • 1 Stop DEN · Denver 3h 16m
      • United Airlines (UA 497)Airbus
        United Airlines (UA 1842)Boeing 737 800
      • United Airlines (UA 497)
        • -
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      • 06:00 DSM
        11:48 SAN
        7Hrs, 48m 1 Stop (DEN)
      • DSMDes Moines Airport 06:00 - SAN 11:48 7h 48m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 06:00
        DENDenver Intl Airport 10:20
      • DENDenver Intl Airport 07:04
        SANSan Diego International Airport 11:48
      • 7h 48m (3h 16m)
      • 1 Stop DEN · Denver 3h 16m
      • United Airlines (UA 497)Boeing 737 800
        United Airlines (UA 1842)Boeing 737 800
      • United Airlines (UA 497)
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      • 06:00 DSM
        11:48 SAN
        7Hrs, 48m 1 Stop (DEN)
      • DSMDes Moines Airport 06:00 - SAN 11:48 7h 48m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 06:00
        DENDenver Intl Airport 10:20
      • DENDenver Intl Airport 07:04
        SANSan Diego International Airport 11:48
      • 7h 48m (3h 16m)
      • 1 Stop DEN · Denver 3h 16m
      • United Airlines (UA 497)Boeing 737 900
        United Airlines (UA 1842)Boeing 737 900
      • United Airlines (UA 497)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 06:00 DSM
        13:08 SAN
        9Hrs, 08m 1 Stop (DEN)
      • DSMDes Moines Airport 06:00 - SAN 13:08 9h 08m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 06:00
        DENDenver Intl Airport 11:40
      • DENDenver Intl Airport 07:04
        SANSan Diego International Airport 13:08
      • 9h 08m (4h 36m)
      • 1 Stop DEN · Denver 4h 36m
      • United Airlines (UA 497)Airbus
        United Airlines (UA 2381)Boeing 737 800
      • United Airlines (UA 497)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 06:50 DSM
        13:00 SAN
        8Hrs, 10m 1 Stop (STL)
      • DSMDes Moines Airport 06:50 - SAN 13:00 8h 10m 1 Stop (STL) Saint Louis
      • DSMDes Moines Airport 06:50
        STLSt Louis Lambert Intl Airport 11:00
      • STLSt Louis Lambert Intl Airport 08:05
        SANSan Diego International Airport 13:00
      • 8h 10m (2h 55m)
      • 1 Stop STL · Saint Louis 2h 55m
      • Southwest Airlines (WN 372)Boeing 737 700
        Southwest Airlines (WN 3648)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 372)
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        • -
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      • 06:55 DSM
        13:47 SAN
        8Hrs, 52m 1 Stop (CLT)
      • DSMDes Moines Airport 06:55 - SAN 13:47 8h 52m 1 Stop (CLT) Charlotte
      • DSMDes Moines Airport 06:55
        CLTCharlotte Airport 11:15
      • CLTCharlotte Airport 10:12
        SANSan Diego International Airport 13:47
      • 8h 52m (1h 03m)
      • 1 Stop CLT · Charlotte 1h 03m
      • American Airlines (AA 2854)Airbus
        American Airlines (AA 466)Airbus
      • American Airlines (AA 2854)
        • -
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        • -
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        • -
        • -
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      • 06:55 DSM
        13:49 SAN
        8Hrs, 54m 1 Stop (CLT)
      • DSMDes Moines Airport 06:55 - SAN 13:49 8h 54m 1 Stop (CLT) Charlotte
      • DSMDes Moines Airport 06:55
        CLTCharlotte Airport 11:21
      • CLTCharlotte Airport 10:12
        SANSan Diego International Airport 13:49
      • 8h 54m (1h 09m)
      • 1 Stop CLT · Charlotte 1h 09m
      • American Airlines (AA 2854)Airbus
        American Airlines (AA 466)Airbus
      • American Airlines (AA 2854)
        • M
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        • F
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      • 07:00 DSM
        11:10 SAN
        6Hrs, 10m 1 Stop (DEN)
      • DSMDes Moines Airport 07:00 - SAN 11:10 6h 10m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 07:00
        DENDenver Intl Airport 09:45
      • DENDenver Intl Airport 08:05
        SANSan Diego International Airport 11:10
      • 6h 10m (1h 40m)
      • 1 Stop DEN · Denver 1h 40m
      • Southwest Airlines (WN 845)Boeing 737 700
        Southwest Airlines (WN 3547)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 845)
        • M
        • -
        • -
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        • F
        • -
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      • 07:00 DSM
        13:10 SAN
        8Hrs, 10m 1 Stop (DEN)
      • DSMDes Moines Airport 07:00 - SAN 13:10 8h 10m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 07:00
        DENDenver Intl Airport 11:45
      • DENDenver Intl Airport 08:05
        SANSan Diego International Airport 13:10
      • 8h 10m (3h 40m)
      • 1 Stop DEN · Denver 3h 40m
      • Southwest Airlines (WN 845)Boeing 737 700
        Southwest Airlines (WN 3097)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 845)
        • M
        • -
        • -
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        • F
        • -
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      • 08:00 DSM
        13:50 SAN
        7Hrs, 50m 1 Stop (IAH)
      • DSMDes Moines Airport 08:00 - SAN 13:50 7h 50m 1 Stop (IAH) Houston
      • DSMDes Moines Airport 08:00
        IAHHouston George Bush Intercontinental Airport 12:20
      • IAHHouston George Bush Intercontinental Airport 10:40
        SANSan Diego International Airport 13:50
      • 7h 50m (1h 40m)
      • 1 Stop IAH · Houston 1h 40m
      • United Airlines (UA 5456)Embraer 175
        United Airlines (UA 2486)Boeing 737 900
      • United Airlines (UA 5456)
        • M
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        • F
        • S
        • S
      • 08:00 DSM
        15:32 SAN
        9Hrs, 32m 1 Stop (ORD)
      • DSMDes Moines Airport 08:00 - SAN 15:32 9h 32m 1 Stop (ORD) Chicago
      • DSMDes Moines Airport 08:00
        ORDChicago O'Hare International Airport 13:02
      • ORDChicago O'Hare International Airport 09:27
        SANSan Diego International Airport 15:32
      • 9h 32m (3h 35m)
      • 1 Stop ORD · Chicago 3h 35m
      • United Airlines (UA 1363)Boeing 737 800
        United Airlines (UA 2683)Boeing 737 800
      • United Airlines (UA 1363)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 08:15 DSM
        11:55 SAN
        5Hrs, 40m 1 Stop (DEN)
      • DSMDes Moines Airport 08:15 - SAN 11:55 5h 40m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 08:15
        DENDenver Intl Airport 10:30
      • DENDenver Intl Airport 09:20
        SANSan Diego International Airport 11:55
      • 5h 40m (1h 10m)
      • 1 Stop DEN · Denver 1h 10m
      • Southwest Airlines (WN 845)Boeing 737 700
        Southwest Airlines (WN 2093)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 845)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 08:15 DSM
        14:40 SAN
        8Hrs, 25m 1 Stop (DEN)
      • DSMDes Moines Airport 08:15 - SAN 14:40 8h 25m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 08:15
        DENDenver Intl Airport 13:15
      • DENDenver Intl Airport 09:20
        SANSan Diego International Airport 14:40
      • 8h 25m (3h 55m)
      • 1 Stop DEN · Denver 3h 55m
      • Southwest Airlines (WN 845)Boeing 737 700
        Southwest Airlines (WN 1706)Boeing 737 700
      • Southwest Airlines (WN 845)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 08:45 DSM
        12:50 SAN
        6Hrs, 05m 1 Stop (DEN)
      • DSMDes Moines Airport 08:45 - SAN 12:50 6h 05m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 08:45
        DENDenver Intl Airport 11:25
      • DENDenver Intl Airport 09:50
        SANSan Diego International Airport 12:50
      • 6h 05m (1h 35m)
      • 1 Stop DEN · Denver 1h 35m
      • Southwest Airlines (WN 845)Boeing 737 700
        Southwest Airlines (WN 2038)Boeing 737 700
      • Southwest Airlines (WN 845)
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        • W
        • -
        • -
        • -
        • -
      • 08:45 DSM
        13:08 SAN
        6Hrs, 23m 1 Stop (DEN)
      • DSMDes Moines Airport 08:45 - SAN 13:08 6h 23m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 08:45
        DENDenver Intl Airport 11:40
      • DENDenver Intl Airport 09:49
        SANSan Diego International Airport 13:08
      • 6h 23m (1h 51m)
      • 1 Stop DEN · Denver 1h 51m
      • United Airlines (UA 581)Airbus
        United Airlines (UA 2381)Boeing 737 Max 8 Passenger
      • United Airlines (UA 581)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 13:50 PHX
        09:50 DEN
        7Hrs, 20m 1 Stop (SAN)
      • PHXPhoenix Sky Harbor Intl Airport 13:50 - DEN 09:50 7h 20m 1 Stop (SAN) San Diego
      • PHXPhoenix Sky Harbor Intl Airport 13:50
        DSMDes Moines Airport 08:45
      • SANSan Diego International Airport 14:05
        DENDenver Intl Airport 09:50
      • 7h 20m (2h)
      • 1 Stop SAN · San Diego 2h
      • Southwest Airlines (WN 2777)Boeing 737 700
        Southwest Airlines (WN 845)Boeing 737 700
      • Southwest Airlines (WN 2777)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 08:45 DSM
        14:35 SAN
        7Hrs, 50m 1 Stop (DEN)
      • DSMDes Moines Airport 08:45 - SAN 14:35 7h 50m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 08:45
        DENDenver Intl Airport 13:10
      • DENDenver Intl Airport 09:50
        SANSan Diego International Airport 14:35
      • 7h 50m (3h 20m)
      • 1 Stop DEN · Denver 3h 20m
      • Southwest Airlines (WN 845)Boeing 737 700
        Southwest Airlines (WN 2807)Boeing 737 700
      • Southwest Airlines (WN 845)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 08:45 DSM
        14:53 SAN
        8Hrs, 08m 1 Stop (DEN)
      • DSMDes Moines Airport 08:45 - SAN 14:53 8h 08m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 08:45
        DENDenver Intl Airport 13:25
      • DENDenver Intl Airport 09:49
        SANSan Diego International Airport 14:53
      • 8h 08m (3h 36m)
      • 1 Stop DEN · Denver 3h 36m
      • United Airlines (UA 581)Airbus
        United Airlines (UA 1302)Boeing 737 800
      • United Airlines (UA 581)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 09:02 DSM
        13:08 SAN
        6Hrs, 06m 1 Stop (DEN)
      • DSMDes Moines Airport 09:02 - SAN 13:08 6h 06m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 09:02
        DENDenver Intl Airport 11:40
      • DENDenver Intl Airport 10:17
        SANSan Diego International Airport 13:08
      • 6h 06m (1h 23m)
      • 1 Stop DEN · Denver 1h 23m
      • United Airlines (UA 581)Airbus
        United Airlines (UA 2381)Boeing 737 Max 8 Passenger
      • United Airlines (UA 581)
        • M
        • T
        • W
        • T
        • F
        • -
        • -
      • 09:02 DSM
        13:08 SAN
        6Hrs, 06m 1 Stop (DEN)
      • DSMDes Moines Airport 09:02 - SAN 13:08 6h 06m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 09:02
        DENDenver Intl Airport 11:40
      • DENDenver Intl Airport 10:17
        SANSan Diego International Airport 13:08
      • 6h 06m (1h 23m)
      • 1 Stop DEN · Denver 1h 23m
      • United Airlines (UA 581)Airbus
        United Airlines (UA 2381)Boeing 737 800
      • United Airlines (UA 581)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 09:02 DSM
        14:53 SAN
        7Hrs, 51m 1 Stop (DEN)
      • DSMDes Moines Airport 09:02 - SAN 14:53 7h 51m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 09:02
        DENDenver Intl Airport 13:25
      • DENDenver Intl Airport 10:17
        SANSan Diego International Airport 14:53
      • 7h 51m (3h 08m)
      • 1 Stop DEN · Denver 3h 08m
      • United Airlines (UA 581)Airbus
        United Airlines (UA 1302)Boeing 737 900
      • United Airlines (UA 581)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 09:02 DSM
        14:53 SAN
        7Hrs, 51m 1 Stop (DEN)
      • DSMDes Moines Airport 09:02 - SAN 14:53 7h 51m 1 Stop (DEN) Denver
      • DSMDes Moines Airport 09:02
        DENDenver Intl Airport 13:25
      • DENDenver Intl Airport 10:17
        SANSan Diego International Airport 14:53
      • 7h 51m (3h 08m)
      • 1 Stop DEN · Denver 3h 08m
      • United Airlines (UA 581)Airbus
        United Airlines (UA 1302)Boeing 737 800
      • United Airlines (UA 581)
        • M
        • -
        • W
        • T
        • F
        • -
        • -
      • 11:25 DSM
        18:51 SAN
        9Hrs, 26m 1 Stop (ORD)
      • DSMDes Moines Airport 11:25 - SAN 18:51 9h 26m 1 Stop (ORD) Chicago
      • DSMDes Moines Airport 11:25
        ORDChicago O'Hare International Airport 16:20
      • ORDChicago O'Hare International Airport 12:53
        SANSan Diego International Airport 18:51
      • 9h 26m (3h 27m)
      • 1 Stop ORD · Chicago 3h 27m
      • United Airlines (UA 2306)Airbus
        United Airlines (UA 1631)Boeing 737 Max 8 Passenger
      • United Airlines (UA 2306)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 11:25 DSM
        18:51 SAN
        9Hrs, 26m 1 Stop (ORD)
      • DSMDes Moines Airport 11:25 - SAN 18:51 9h 26m 1 Stop (ORD) Chicago
      • DSMDes Moines Airport 11:25
        ORDChicago O'Hare International Airport 16:20
      • ORDChicago O'Hare International Airport 12:53
        SANSan Diego International Airport 18:51
      • 9h 26m (3h 27m)
      • 1 Stop ORD · Chicago 3h 27m
      • United Airlines (UA 2306)Airbus
        United Airlines (UA 1631)Boeing 737 Max 8 Passenger
      • United Airlines (UA 2306)
        • M
        • -
        • W
        • T
        • F
        • -
        • -
      • 11:25 DSM
        18:51 SAN
        9Hrs, 26m 1 Stop (ORD)
      • DSMDes Moines Airport 11:25 - SAN 18:51 9h 26m 1 Stop (ORD) Chicago
      • DSMDes Moines Airport 11:25
        ORDChicago O'Hare International Airport 16:20
      • ORDChicago O'Hare International Airport 12:56
        SANSan Diego International Airport 18:51
      • 9h 26m (3h 24m)
      • 1 Stop ORD · Chicago 3h 24m
      • United Airlines (UA 3597)Embraer 170
        United Airlines (UA 1631)Boeing 737 Max 8 Passenger
      • United Airlines (UA 3597)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 11:25 DSM
        18:51 SAN
        9Hrs, 26m 1 Stop (ORD)
      • DSMDes Moines Airport 11:25 - SAN 18:51 9h 26m 1 Stop (ORD) Chicago
      • DSMDes Moines Airport 11:25
        ORDChicago O'Hare International Airport 16:20
      • ORDChicago O'Hare International Airport 12:56
        SANSan Diego International Airport 18:51
      • 9h 26m (3h 24m)
      • 1 Stop ORD · Chicago 3h 24m
      • United Airlines (UA 3597)Embraer 175
        United Airlines (UA 1631)Boeing 737 900
      • United Airlines (UA 3597)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 11:29 DSM
        15:55 SAN
        6Hrs, 26m 1 Stop (DFW)
      • DSMDes Moines Airport 11:29 - SAN 15:55 6h 26m 1 Stop (DFW) Dallas
      • DSMDes Moines Airport 11:29
        DFWDallas/Fort Worth Intl Airport 14:41
      • DFWDallas/Fort Worth Intl Airport 13:45
        SANSan Diego International Airport 15:55
      • 6h 26m (56m)
      • 1 Stop DFW · Dallas 56m
      • American Airlines (AA 3743)Embraer Emb 175
        American Airlines (AA 2361)Airbus
      • American Airlines (AA 3743)
        • M
        • T
        • -
        • -
        • -
        • -
        • -
      • 11:29 DSM
        15:55 SAN
        6Hrs, 26m 1 Stop (DFW)
      • DSMDes Moines Airport 11:29 - SAN 15:55 6h 26m 1 Stop (DFW) Dallas
      • DSMDes Moines Airport 11:29
        DFWDallas/Fort Worth Intl Airport 14:41
      • DFWDallas/Fort Worth Intl Airport 13:38
        SANSan Diego International Airport 15:55
      • 6h 26m (1h 03m)
      • 1 Stop DFW · Dallas 1h 03m
      • American Airlines (AA 1286)Airbus
        American Airlines (AA 2361)Airbus
      • American Airlines (AA 1286)
        • -
        • -
        • -
        • T
        • F
        • S
        • S
      • 11:29 DSM
        18:16 SAN
        8Hrs, 47m 1 Stop (DFW)
      • DSMDes Moines Airport 11:29 - SAN 18:16 8h 47m 1 Stop (DFW) Dallas
      • DSMDes Moines Airport 11:29
        DFWDallas/Fort Worth Intl Airport 17:03
      • DFWDallas/Fort Worth Intl Airport 13:38
        SANSan Diego International Airport 18:16
      • 8h 47m (3h 25m)
      • 1 Stop DFW · Dallas 3h 25m
      • American Airlines (AA 1286)Airbus
        American Airlines (AA 1948)Airbus
      • American Airlines (AA 1286)
        • -
        • -
        • -
        • T
        • F
        • S
        • S
      • 11:29 DSM
        18:16 SAN
        8Hrs, 47m 1 Stop (DFW)
      • DSMDes Moines Airport 11:29 - SAN 18:16 8h 47m 1 Stop (DFW) Dallas
      • DSMDes Moines Airport 11:29
        DFWDallas/Fort Worth Intl Airport 17:03
      • DFWDallas/Fort Worth Intl Airport 13:45
        SANSan Diego International Airport 18:16
      • 8h 47m (3h 18m)
      • 1 Stop DFW · Dallas 3h 18m
      • American Airlines (AA 3743)Embraer Emb 175
        American Airlines (AA 1948)Airbus
      • American Airlines (AA 3743)
        • M
        • T
        • -
        • -
        • -
        • -
        • -
      • 11:50 DSM
        16:20 SAN
        6Hrs, 30m 1 Stop (PHX)
      • DSMDes Moines Airport 11:50 - SAN 16:20 6h 30m 1 Stop (PHX) Phoenix
      • DSMDes Moines Airport 11:50
        PHXPhoenix Sky Harbor Intl Airport 16:05
      • PHXPhoenix Sky Harbor Intl Airport 14:00
        SANSan Diego International Airport 16:20
      • 6h 30m (2h 05m)
      • 1 Stop PHX · Phoenix 2h 05m
      • Southwest Airlines (WN 2269)Boeing 737 800
        Southwest Airlines (WN 4122)Boeing 737 700
      • Southwest Airlines (WN 2269)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 11:50 DSM
        17:20 SAN
        7Hrs, 30m 1 Stop (PHX)
      • DSMDes Moines Airport 11:50 - SAN 17:20 7h 30m 1 Stop (PHX) Phoenix
      • DSMDes Moines Airport 11:50
        PHXPhoenix Sky Harbor Intl Airport 17:10
      • PHXPhoenix Sky Harbor Intl Airport 14:00
        SANSan Diego International Airport 17:20
      • 7h 30m (3h 10m)
      • 1 Stop PHX · Phoenix 3h 10m
      • Southwest Airlines (WN 2269)Boeing 737 800
        Southwest Airlines (WN 4355)Boeing 737 700
      • Southwest Airlines (WN 2269)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 12:25 DSM
        16:05 SAN
        5Hrs, 40m 1 Stop (LAS)
      • DSMDes Moines Airport 12:25 - SAN 16:05 5h 40m 1 Stop (LAS) Las Vegas
      • DSMDes Moines Airport 12:25
        LASLas Vegas McCarran International Airport 14:50
      • LASLas Vegas McCarran International Airport 13:35
        SANSan Diego International Airport 16:05
      • 5h 40m (1h 15m)
      • 1 Stop LAS · Las Vegas 1h 15m
      • Southwest Airlines (WN 2269)Boeing 737 800
        Southwest Airlines (WN 1393)Boeing 737 700
      • Southwest Airlines (WN 2269)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 12:25 DSM
        17:45 SAN
        7Hrs, 20m 1 Stop (LAS)
      • DSMDes Moines Airport 12:25 - SAN 17:45 7h 20m 1 Stop (LAS) Las Vegas
      • DSMDes Moines Airport 12:25
        LASLas Vegas McCarran International Airport 16:30
      • LASLas Vegas McCarran International Airport 13:35
        SANSan Diego International Airport 17:45
      • 7h 20m (2h 55m)
      • 1 Stop LAS · Las Vegas 2h 55m
      • Southwest Airlines (WN 2269)Boeing 737 800
        Southwest Airlines (WN 2623)Boeing 737 700
      • Southwest Airlines (WN 2269)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
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      How far is San Diego from Des Moines?

      The flight distance between Des Moines and San Diego is 2299km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 05:00. The last flight of the day departs at 18:15. See the full list of flight times on Wego.

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      Des Moines Airport DSM

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